From Chhatrapati Shivaji Maharaj International and Domestic airport

45-90 minutes by taxi.
Pre-paid taxis are the recommended way of reaching TIFR from Mumbai's airports. There are counters for pre-paid taxis before you exit the arrival hall. Specify your destination as "Navy Nagar, Colaba".
You will be given a receipt for your payment. Retain this till the end of your ride; then hand it over to the taxi driver. At the exit from the airport, the police may want to look at this slip.

From Chhatrapati Shivaji Maharaj Terminus (CSMT) railway station

20-30 mins by taxi.
Taxis are available from the Chhatrapati Shivaji Maharaj Terminus (CSMT). They charge by meter. Alternatively, one can board buses to Navy Nagar (bus terminal) from outside the local railway station at CSMT. TIFR is on the same road as the Navy Nagar bus terminus, which is where you should get off.

From Mumbai Central (BCT) railway station

30-45 mins by taxi.
Taxis are available from the ranks outside the railway station. Alternatively, you could cross over to the local railway station and board a Churchgate bound local. You have to buy a separate ticket for the local train. Taxis are available from outside Churchgate. Alternately, a bus (route 137) comes from Churchgate to the Navy Nagar bus terminus, down the road from TIFR.

From Lokmanya Tilak Terminus (LTT) railway station

45-60 mins by taxi.
Taxis are available from the ranks outside the railway station. Alternatively, you could walk over to the local railway station Tilak Nagar and board a CSMT bound local. You have to buy a separate ticket for the local train. Taxis are available from outside CSMT. Alternately, one can board BEST buses from CSMT to the Navy Nagar bus terminus, down the road from TIFR.

From Bandra Terminus railway station

60-90 mins by taxi.
Taxis are available from the ranks outside the railway station. Alternatively, you could walk over to the local bandra railway station and board a Churchgate local train. You have to buy a separate ticket for the local train. Taxis are available from outside churchgate. Alternately, a bus (route 137) comes from Churchgate to the Navy Nagar bus terminus, down the road from TIFR.